ODESSA: A high performance analysis pipeline for Ultra Deep targeted Exome Sequencing data

M. D'Antonio, P. D'Onorio De Meo, T. Castrignano, G. Erbacci (Cineca); M. Pallocca (IRE); G. Pesole (CNR)

The last decade has seen the development of a variety of so-called ‘next-generation’ sequencing (NGS) technologies, that have revolutionized the field of genomics and post-genomics. In cancer research area, as NGS permeates the cancer biomarker realm and cost of NGS declines, hospitals and clinics will deploy deep sequencing as a means to personalize cancer diagnostics and therapeutics. Here we provide a new automated high-performance bioinformatics web platform, ODESSA (Online Deep Exome Sequencing Software Analysis), developed for targeting genes at high coverage through deep sequencing with the maximum usability, and focused on rational diagnosis of targeted therapies.

Published in:High Performance Computing & Simulation (HPCS), 2014 International Conference on
Date of Conference: 21-25 July 2014
Page(s): 608 - 615
Print ISBN: 978-1-4799-5312-7
Conference Location: Bologna, Italy
DOI: 10.1109/HPCSim.2014.6903743
Publisher: IEEE